Our laboratory at the University of São Paulo is dedicated to understanding the chemical signals that regulate the development of Plasmodium falciparum , the etiologic agent of malaria.

The disease is one of the most critical health problems that affects half a billion people and kills almost a million individuals annually. The resistance of the parasite to classical drugs as chloroquine is posing an urgency in finding new drugs to combat the disease.

To achieve our goals, we work on biochemistry and molecular biology techniques by generating knockouts of genes involved in signaling pathways combining with live-cell microscopy. Our laboratory is also set up for the screening of chemical compounds focusing on the development of new drugs to treat malaria.

Celia Regina da Silva Garcia, Ph.D
Professor
Department of Clinical and Toxicological Analyses
School of Pharmaceutical Sciences, University of São Paulo
Email: cgarcia@usp.br

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